ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2
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چکیده
منابع مشابه
ETO family protein Mtg16 regulates the balance of dendritic cell subsets by repressing Id2
Dendritic cells (DCs) comprise two major subsets, the interferon (IFN)-producing plasmacytoid DCs (pDCs) and antigen-presenting classical DCs (cDCs). The development of pDCs is promoted by E protein transcription factor E2-2, whereas E protein antagonist Id2 is specifically absent from pDCs. Conversely, Id2 is prominently expressed in cDCs and promotes CD8(+) cDC development. The mechanisms tha...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2014
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.20132121